The most famous river in America runs like a spine between the eastern and western parts of the country, flowing through ten states before it empties into the Gulf of Mexico. The mighty Miss also flows through the history of America, giving rise to great stories about the people who lived on it and used it as a watery highway, from Native Americans and European explorers to skillful riverboat captains and colorful gamblers traveling on luxurious steamboats. And of course it was the first truly American writer, Mark Twain, who grew up along its banks and made the Mississippi River famous around the world.